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Circulation, 111, 3400в3410. пппппппп Page 274 Page 278 101111001 291 Page 1265 Page 474 5. Von Willebrand disease is an autosomal-dominant condition with considerable molecular and clinical heteroge- neity. 203 In addition, p85ОPI3 ki- nase has writte n been implicated in membrane ruffling induced by PDGF204 and IGF-1.

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